Santyl (Advance Biofactures Corp)

Santyl (Advance Biofactures Corp) - General Information

The enzyme collagenase is derived from fermentation of Clostridium histolyticum

Pharmacology of Santyl (Advance Biofactures Corp)

Used in the treatment of skin ulcers and sever burns, collagenase is able to digest collagen in necrotic tissue at physiological pH. Santyl (Advance Biofactures Corp) thus contributes towards the formation of granulation tissue and subsequent epithelization of dermal ulcers and severely burned areas.

Santyl (Advance Biofactures Corp) for patients

Santyl (Advance Biofactures Corp) Interactions

Santyl (Advance Biofactures Corp) Contraindications

Collagenase Santyl^® Ointment is contraindicated in patients who have shown local or systemic hypersensitivity to collagenase.

Additional information about Santyl (Advance Biofactures Corp)

Santyl (Advance Biofactures Corp) Indication: For treatment of chronic dermal ulcers and severe skin burns
Mechanism Of Action: Santyl (Advance Biofactures Corp) is a protease that is specific to collagen. The triple helical region of interstitial collagens is highly resistant to most cell proteinases. However, during remodeling of the connective tissue in such processes as wound healing and metastasis, collagen becomes susceptible to cleavage by collagenases. Santyl (Advance Biofactures Corp) cleaves all 3 alpha helical chains of native Types I, II and III collagens at a single locus by hydrolyzing the peptide bond following the Gly residue of the sequence: Gly 775-(Ile or Leu) 776-(Ala or Leu) 777 located approximately three-fourths of the chain length from each N-terminus
Drug Interactions: Not Available
Food Interactions: Not Available
Generic Name: Collagenase
Synonyms: Not Available
Drug Category: Anti-Ulcer Agents; Topical
Drug Type: Biotech; Approved

Other Brand Names containing Collagenase: Santyl (Advance Biofactures Corp);
Absorption: Not Available
Toxicity (Overdose): Not Available
Protein Binding: Not Available
Biotransformation: Not Available
Half Life: Not Available
Dosage Forms of Santyl (Advance Biofactures Corp): Ointment Topical
Chemical IUPAC Name: Clostridium histolyticum collagenase
Chemical Formula: C5028H7666N1300O1564S21
Collagenase on Wikipedia: https://en.wikipedia.org/wiki/Collagenase
Organisms Affected: Humans and other mammals